Product Details
»Book Publisher: Springer (31 January, 2003)
»ISBN: 0306474417
»Book author: Marek Los, Henning Walczak
Book Description:
The volume offers insight into the key research topics that involve caspases. Leading experts from various areas of biology and medicine have compiled this volume so that both the novice and the professional will use this as the main reference for caspases for years to come. The reader will learn about the role of caspases in apoptosis signaling, inflammation and cancer therapy while being updated on the methodology used to study caspases and the efforts of pharmaceutical research in targeting caspases.
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Product Details
»Book Publisher: Humana Press (09 December, 2002)
»ISBN: 1588290751
»Book author: David M. Terrian
»Amazon Rating:
Book Description:
A collection of readily reproducible experimental methods for studying the subversion of normal cell signaling that leads to cancer. Presented in step-by-step detail to ensure successful results, the methods include proven techniques for the investigation of apoptosis and cell death, complementary protocols for manipulating and/or monitoring oncogenic signals in cancer cells, and techniques for studying protein-protein interactions. A detailed protocol for capturing pure samples of malignant cells from frozen tissue specimens and two alternative techniques for analyzing their genomic DNA is also described.
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Product Details
»Book Publisher: Humana Press (03 December, 2002)
»ISBN: 089603982X
»Book author: Janusz W. Rak
Book Description:
Prominent investigators and clinicians summarize in a balanced blend of fundamental science, basic research, experimental therapeutics, and early clinical experiences, what is known about oncogenes and oncogenesis, and describe how that knowledge can be used to treat the cancer. The contributors explain how, why, and under what conditions certain proteins acquire the ability to transform eukaryotic cells, and detail the crucial biological consequences of this oncogenic transformation, particularly for cellular mitogenesis, survival, differentiation, migration, proteolysis, or angiogenic competence. Their articles thoroughly explicate the premises, principles, techniques, and approaches to oncogene targeting in various types of human cancer by using signal transduction inhibitors, immunological targeting methods, and antisense gene therapy.
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Product Details
»Book Publisher: Humana Press (15 June, 2002)
»ISBN: 1588290220
»Book author: Eyal, Ed. Raz
Book Description:
Leading researchers review the activation of the mammalian immune system by bacterial DNA and its immunostimulatory sequences (ISS), and consider the applications of ISS in clinical medicine. The authors survey the latest findings concerning the receptor-recognition and signaling pathways triggered by ISS , the process of cell activation, and the potential vaccination strategies using ISS. Specific pharmaceutical applications discussed include infectious disease (Hepatitis B, HIV, and mycobacterial infections), allergy (asthma and conjunctivitis), cancer (lymphoma), and inflammation and autoimmunity (arthritis and colitis).
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Product Details
»Book Publisher: Lippincott Williams & Wilkins (15 December, 2001)
»ISBN: 0781726581
»Book author: Philip A Pizzo, David G Poplack
Book Description:
The definitive reference on pediatric oncology is now in its thoroughly revised, updated Fourth Edition. A multidisciplinary group of the world’s foremost specialists presents state-of-the-art information and guidelines on every aspect of pediatric cancer–from molecular biology to diagnosis, multimodal therapy, and supportive care. This edition features greater integration of the biologic and genetic factors affecting diagnosis and treatment. New chapters discuss incidence and trends in childhood cancer, evolving molecular and targeted therapies, and training strategies to develop humanistic skills in the pediatric hematologist-oncologist. Also included are up-to-date listings of support resources for children with cancer and for their families and physicians. A Brandon-Hill recommended title.
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Product Details
»Book Publisher: Humana Press (15 June, 2001)
»ISBN: 0896039552
»Book author: Ricardo V. Lloyd
Book Description:
Ricardo Lloyd, md, phd, provides critical and tutorial surveys of the cutting-edge molecular and cell biologic techniques used today in the analysis of cells and tissues in situ. These molecular-based histologic and morphologic techniques are described in step-by-step detail by hands-on experts, often those who have originated or perfected them. Among the techniques presented are laser capture microdissection, in situ hybridization, FISH, confocal laser scanning microscopy, in situ PCR, and tyramide amplification. Applications include the detection of infectious agents and DNA, the diagnosis of undifferentiated tumors and endocrine lesions, the metaphase analysis of whole blood cultures, and clonality analysis. In its integrated, state-of-the-art approach, Morphology Methods: Cell and Molecular Biology Techniques thoroughly details and applies the rich panoply of significant new cell and molecular biologic technologies to all the major problems confronting morphologic studies and diagnostic pathology today.
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