Product Details
»Book Publisher: Humana Press (24 June, 2004)
»ISBN: 1588295001
»Book author: Axel H. Schönthal
Book Description:
Prestigious researchers from ten different countries present readily reproducible experimental protocols to study the molecular components of checkpoint controls and their regulation. Described in step-by-step detail, these cutting-edge techniques offer novel approaches, such as the use of genome databases and siRNA, to analyzing how cells of the human body can escape proper surveillance to grow into a tumor. Additional experimental methods are provided for the manipulation of checkpoint pathways and the analysis of the resulting consequences for the cellular phenotype. An earlier first volume, Reviews and Model Systems, comprehensively reviews the complexities of checkpoint controls and the model systems needed to study them.
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Checkpoint Controls and Cancer: Volume 2: Activation and Regulation Protocols (Methods in Molecular Biology)
Posted by arachnoid at 7:47 PMLabels: Molecular Biology, Oncology
»Book Publisher: Wiley (14 June, 2004)
»ISBN: 0471499390
»Book author: Shulamith Kreitler, Myriam Weyl Ben Arush
Book Description:
This book is a comprehensive text on the all-important psychosocial aspects of cancer in children. Edited by an experienced psycho-oncologist and an equally experienced pediatric oncologist, the book brings together an international group of contributors composed of pediatric oncologists and psychologists/psycho-oncologists. This unique balance of contributors gives the book a focus on the real-life practical aspects of children undergoing treatment for cancer. The book helps health care professionals, who look after children and adolescents with cancer, in dealing with the difficult and complex problems that face the child, his siblings and his parents. It deals with critical issues such as the neuropsychological impact of treatment, (including bone marrow transplantation), pain, quality of life in survivors, palliative care, talking to children and their families about death, and providing support to the dying.
An important part of the book provides tools for evaluation and methods of psychological intervention. It is thus a very practical work for psycho-oncologists, pediatric oncologists, pediatricians, psychologists, nurses, social workers and art therapists dealing with the problems that children with cancer have to confront.
- A comprehensive book on the clinical approach to psychosocial problems of children with cancer
- Includes evaluation tools and psychological intervention techniques
- Contributions from both pediatric oncologists and psycho-oncologists highlight the team approach to the treatment of childhood cancers
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Product Details
»Book Publisher: Oxford University Press, USA (26 February, 2004)
»ISBN: 0195144384
»Book author: Rebecca DelCarmen-Wiggins, Alice Carter
Book Description:
The Handbook of Infant, Toddler, and Preschool Mental Health Assessment brings together, for the first time, leading clinical researchers to provide empirically based recommendations for assessment of social-emotional and behavior problems and disorders in the earliest years. Each author presents state-of-the-art information on scientifically valid, developmentally based clinical assessments and makes recommendations based on the integration of developmental theory, empirical findings, and clinical experience. Though the field of mental health assessment in infants and young children lags behind work with older children and adults, recent scientific advances, including new measures and diagnostic approaches, have led to dramatic growth in the field. The editors of this exciting new work have assembled an extraordinary collection of chapters that thoroughly discuss the conceptualizations of dysfunction in infants and young children, current and new diagnostic criteria, and such specific disorders as sensory modulation dysfunction, sleep disorders, eating and feeding disorders, autistic spectrum disorders, anxiety disorders, posttraumatic stress disorder, and ADHD. Chapters further highlight the importance of incorporating contextual factors such as parent-child relationship functioning and cultural background into the assessment process to increase the validity of findings. Given the comprehensiveness of this groundbreaking volume in reviewing conceptual, methodological, and research advances on early identification, diagnosis, and clinical assessment of disorders in this young age group, it will be an ideal resource for teachers, researchers, and a wide variety clinicians including child psychologists, child psychiatrists, early intervention providers, early special educators, social workers, family physicians, and pediatricians.
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»Book Publisher: University Press of Mississippi (January, 2004)
»ISBN: 1578065739
»Book author: Nathan Lavid
Book Description:
Insight into an ailment that impairs more than sixty million in the world population.
Review:
Excellent insight into a prevalent affliction
Dr. Lavid has written an important contribution to this field. One of the difficulties in apprending stuttering in a complete way is its inherent complexity. Such understanding requires a level of familiarity with interactions between psychological,anatomical, physiological and molecular aspects. These areas are managed superbly by the author; each area is presented concisely with an extent of coverage which will satisfy most readers. For those who wish additional information, sources are provided. An excellent guide to assist those who will be conversing with children and adults who stutter is presented and is extremely valuable.
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Labels: Pediatrics, Psychiatry
Pediatric Hematology: Methods and Protocols (Methods in Molecular Medicine volume 91)
Posted by arachnoid at 8:08 PMProduct Details
»Book Publisher: Humana Press (29 September, 2003)
»ISBN: 1588290433
»Book author: Nicholas J. Goulden, Colin G. Steward
Book Description:
A collection of cutting-edge methods for investigating and detecting a wide variety of hematological disorders. Here, the reader will find reliable molecular protocols for the diagnosis of Fanconi anemia and dyskeratosis congenita, immunodeficiency, and most forms of hemoglobinopathy. In addition, there are detailed methods for molecular human platelet antigen genotyping, an effective PCR procedure for thrombophilia screening, and protocols for fluorescent in situ hybridization. Since the measurement of minimal residual disease (MRD) provides a much more accurate risk-directed therapy, three methods are presented for detecting residual leukemia below the threshold of light microscopy, along with relatively simple, rapid, and cheap methods for the detection of MRD in ALL and AML.
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Labels: Haematology, Laboratory, Pediatrics
Product Details
»Book Publisher: Oxford University Press (2003)
»ISBN: 0195154363
»Book author: Rowland H. Davis
Book Description:
This book explains the role of simple biological model systems in the growth of molecular biology. Essentially the whole history of molecular biology is presented here, tracing the work in bacteriophages in E. coli, the role of other prokaryotic systems, and also the protozoan and algal models - Paramecium and Chlamydomonas, primarily - and the move into eukaryotes with the fungal systems - Neurospora, Aspergillus and yeast. Each model was selected for its appropriateness for asking a given class of questions, and each spawned its own community of investigators. Some individuals made the transition to a new model over time, and remnant communities of investigators continue to pursue questions in all these models, as the cutting edge of molecular biological research flowed onward from model to model, and onward into higher organisms and, ultimately, mouse and man.
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Labels: Genetics, Molecular Biology
Tumor Suppressor Genes: Volume 2: Regulation, Function, and Medicinal Applications (Methods in Molecular Biology)
Posted by arachnoid at 7:29 PM»Book Publisher: Humana Press (21 April, 2003)
»ISBN: 0896039870
»Book author: Wafik S. El-Deiry
Book Description:
The second volume of Tumor Suppressor Genes explores the cell biology and biochemical function of the tumor suppressor genes, as well as its physiological role in vivo. The authors detail the physical methods (NMR, microarray approaches, pot-translational structure analysis, analysis of regulation at the gene expression and protein signaling levels)used to understand the function of tumor suppressor genes. In vivo approaches discussed include studies in yeast, Drosophilia, mice, and human tumors.
For both volumes:
Leading physician scientists and academic researchers review all the known tumor suppressor genes, explain how they work, and describe how they were discovered and isolated. In many cases, the authors discuss specific genes that are frequently involved in hereditary or sporadic cancers. They also provide a detailed guide to using powerful molecular genetic, cytogenetic, proteomic, and cell biological strategies to discover and isolate novel tumor suppressor genes and their targets. A second volume of this two-volume set, Tumor Suppressor Genes, Volume 2: Regulation, Function, and Medical Applications, shows how to explore the cell biology and biochemical function of such encoded proteins, to study its physiological role in vivo, and to use information on TSGs to develop diagnostic and therapeutic strategies for cancer.
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Labels: Biochemistry, Biology, Molecular Biology, Oncology